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HDAC4 antibody (AA 456-592)

The Mouse Monoclonal anti-HDAC4 antibody has been validated for ELISA, ICC and FACS. It is suitable to detect HDAC4 in samples from Human.
Catalog No. ABIN5542326

Quick Overview for HDAC4 antibody (AA 456-592) (ABIN5542326)

Target

See all HDAC4 Antibodies
HDAC4 (Histone Deacetylase 4 (HDAC4))

Reactivity

  • 119
  • 49
  • 35
  • 6
  • 6
  • 4
  • 4
  • 4
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  • 2
  • 2
  • 1
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Human

Host

  • 108
  • 13
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Mouse

Clonality

  • 105
  • 17
Monoclonal

Conjugate

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  • 2
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  • 2
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  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This HDAC4 antibody is un-conjugated

Application

  • 83
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  • 4
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ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone

7E2E6
  • Binding Specificity

    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
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    AA 456-592

    Purpose

    HDAC4 Antibody

    Purification

    Purified antibody

    Immunogen

    Purified recombinant fragment of human HDAC4 (AA: 456-592) expressed in E. Coli.

    Isotype

    IgG1
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target

    HDAC4 (Histone Deacetylase 4 (HDAC4))

    Alternative Name

    HDAC4

    Background

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

    Molecular Weight

    119 kDa

    Gene ID

    9759

    UniProt

    P56524

    Pathways

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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