HDAC4 antibody (AA 1049-1077)
Quick Overview for HDAC4 antibody (AA 1049-1077) (ABIN3031231)
Target
See all HDAC4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1049-1077
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Purpose
- HDAC4 Antibody
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 1049-1077 from the human protein was used as the immunogen for this HDAC4 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the HDAC4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Aliquot the HDAC4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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Alternative Name
- HDAC4
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Background
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
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UniProt
- P56524
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
Target
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