HDAC6 antibody (AA 482-800)
Quick Overview for HDAC6 antibody (AA 482-800) (ABIN5542328)
Target
See all HDAC6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
 - AA 482-800
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Purpose
 - HDAC6 Antibody
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Purification
 - Purified antibody
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Immunogen
 - Purified recombinant fragment of human HDAC6 (AA: 482-800) expressed in E. Coli.
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Isotype
 - IgG2b
 
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
 - For Research Use only
 
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Format
 - Liquid
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Buffer
 - Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
 - Sodium azide
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Precaution of Use
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - 4 °C,-20 °C
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Storage Comment
 - Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Alternative Name
 - HDAC6
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Background
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                        Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. 
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Molecular Weight
 - 131.4 kDa
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UniProt
 - Q9UBN7
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Pathways
 - Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
 
Target
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