RAD18 antibody (AA 332-430)

Catalog No. ABIN5542377

The Mouse Monoclonal anti-RAD18 antibody has been validated for ELISA and FACS. It is suitable to detect RAD18 in samples from Human.

Quick Overview for RAD18 antibody (AA 332-430) (ABIN5542377)

Target: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAD18 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 2G8C10

Product Details anti-RAD18 Antibody

Binding Specificity: AA 332-430

Purpose: RAD18 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RAD18 (AA: 332-430) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for RAD18

Target: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Alternative Name: RAD18

Background: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

Molecular Weight: 56.2 kDa

Gene ID: 56852

UniProt: Q9NS91