Neuropilin 1 antibody (AA 45-59)
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- Target See all Neuropilin 1 (NRP1) Antibodies
- Neuropilin 1 (NRP1)
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Binding Specificity
- AA 45-59
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Neuropilin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purpose
- Neuropilin-1 Antibody
- Purification
- Purified antibody
- Immunogen
- Synthesized peptide of human Neuropilin-1 (AA: 45-59).
- Clone
- 5B1E11
- Isotype
- IgG1
- Top Product
- Discover our top product NRP1 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Neuropilin 1 (NRP1)
- Alternative Name
- Neuropilin-1 (NRP1 Products)
- Background
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This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
- Molecular Weight
- 103.1 kDa
- Gene ID
- 8829
- UniProt
- O14786
- Pathways
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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