OB Cadherin antibody (AA 468-617)

Catalog No. ABIN5542424

This Mouse Monoclonal antibody specifically detects OB Cadherin in ELISA, IHC, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for OB Cadherin antibody (AA 468-617) (ABIN5542424)

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OB Cadherin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 4E12G10

Product Details anti-OB Cadherin Antibody

Binding Specificity: AA 468-617

Purpose: CDH11 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CDH11 (AA: 468-617) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for OB Cadherin

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Alternative Name: CDH11

Background: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Molecular Weight: 88 kDa

UniProt: P55287