OB Cadherin antibody (AA 468-617)

Catalog No. ABIN5542425

The Mouse Monoclonal anti-OB Cadherin antibody has been validated for WB, ELISA, IHC, ICC and FACS. It is suitable to detect OB Cadherin in samples from Human.

Quick Overview for OB Cadherin antibody (AA 468-617) (ABIN5542425)

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OB Cadherin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 2C12A6

Product Details anti-OB Cadherin Antibody

Binding Specificity: AA 468-617

Purpose: CDH11 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CDH11 (AA: 468-617) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for OB Cadherin

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Alternative Name: CDH11

Background: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Molecular Weight: 88 kDa

UniProt: P55287