SIRT4 antibody (AA 215-314)

Catalog No. ABIN5542440

The Mouse Monoclonal anti-SIRT4 antibody has been validated for ELISA, ICC and FACS. It is suitable to detect SIRT4 in samples from Human.

Quick Overview for SIRT4 antibody (AA 215-314) (ABIN5542440)

Target: SIRT4 (Sirtuin 4 (SIRT4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIRT4 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 6G6D2

Product Details anti-SIRT4 Antibody

Binding Specificity: AA 215-314

Purpose: SIRT4 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SIRT4 (AA: 215-314) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/100 - 1/500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for SIRT4

Target: SIRT4 (Sirtuin 4 (SIRT4))

Alternative Name: SIRT4

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Molecular Weight: 35.2 kDa

UniProt: Q9Y6E7

Pathways: Negative Regulation of Hormone Secretion