ESRRA antibody (AA 198-376)

Catalog No. ABIN5542453

This anti-ESRRA antibody is a Mouse Monoclonal antibody detecting ESRRA in WB, ELISA and FACS. Suitable for Human and Rat.

Quick Overview for ESRRA antibody (AA 198-376) (ABIN5542453)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ESRRA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 6F1E6

Product Details anti-ESRRA Antibody

Binding Specificity: AA 198-376

Purpose: ESRRA Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ESRRA (AA: 198-376) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Alternative Name: ESRRA

Background: The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 45.5 kDa

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha