JARID2 antibody (AA 1097-1246)

Catalog No. ABIN5542458

The Mouse Monoclonal anti-JARID2 antibody has been validated for ELISA, ICC and FACS. It is suitable to detect JARID2 in samples from Human.

Quick Overview for JARID2 antibody (AA 1097-1246) (ABIN5542458)

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JARID2 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 7H1B3

Product Details anti-JARID2 Antibody

Binding Specificity: AA 1097-1246

Purpose: JARID2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human JARID2 (AA: 1097-1246) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for JARID2

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Alternative Name: JARID2

Background: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.

Molecular Weight: 139 kDa

UniProt: Q92833

Pathways: Chromatin Binding