UBE2C antibody (AA 1-179)

Catalog No. ABIN5542503

The Mouse Monoclonal anti-UBE2C antibody has been validated for ELISA and IHC. It is suitable to detect UBE2C in samples from Human.

Quick Overview for UBE2C antibody (AA 1-179) (ABIN5542503)

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UBE2C antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: 1F5D3

Product Details anti-UBE2C Antibody

Binding Specificity: AA 1-179

Purpose: UBE2C Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human UBE2C (AA: FULL(1-179)) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for UBE2C

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Alternative Name: UBE2C

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.

Molecular Weight: 19.7 kDa

UniProt: O00762

Pathways: Ubiquitin Proteasome Pathway