UHRF1 antibody (AA 616-755)
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- Target See all UHRF1 Antibodies
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
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Binding Specificity
- AA 616-755
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This UHRF1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purpose
- UHRF1 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human UHRF1 (AA: 616-755) expressed in E. Coli.
- Clone
- 2A8C7
- Isotype
- IgG1
- Top Product
- Discover our top product UHRF1 Primary Antibody
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anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 616-755) antibody
UHRF1 Reactivity: Human WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 1A1B1 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 1-260) antibodyUHRF1 Reactivity: Human WB, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 694-793) antibodyUHRF1 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3A11 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 229-257) antibodyUHRF1 Reactivity: Human WB, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (N-Term) antibodyUHRF1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC, IP, ICC, ChIP Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 229-257) antibodyUHRF1 Reactivity: Human WB, IF, FACS Host: Rabbit Polyclonal RB21516 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibodyKO Validated UHRF1 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 596-628), (C-Term) antibodyUHRF1 Reactivity: Mouse WB Host: Rabbit Polyclonal RB51453 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (meLys385) antibodyUHRF1 Reactivity: Human WB, IHC, DB Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibodyUHRF1 Reactivity: Human WB, FACS, IF/ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
- Alternative Name
- UHRF1 (UHRF1 Products)
- Background
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Description: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12.
Aliases: Np95, hNP95, ICBP90, RNF106, TDRD22, hUHRF1, huNp95
- Molecular Weight
- 89.8kDa
- Gene ID
- 29128
- HGNC
- 5335
- UniProt
- Q96T88
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