UHRF1 antibody (AA 694-793)

Catalog No. ABIN565416

Cited in 2+ publications. The Mouse Monoclonal anti-UHRF1 antibody (Clone 3A11) (ABIN565416) specifically detects UHRF1 in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for UHRF1 antibody (AA 694-793) (ABIN565416)

Target: UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UHRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 3A11

Product Details anti-UHRF1 Antibody

Binding Specificity: AA 694-793

Purpose: Mouse monoclonal antibody raised against a partial recombinant UHRF1.

Sequence: WNEVLASLKD RPASGSPFQL FLSKVEETFQ CICCQELVFR PITTVCQHNV CKDCLDRSFR AQVFSCPACR YDLGRSYAMQ VNQPLQTVLN QLFPGYGNGR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: UHRF1 (NP_037414, 694 a.a. ~ 793 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-UHRF1 antibody (ABIN565416)

Du, Song, Wang, Zhao, Guda, Yang, Kao, Xu, Willis, Markowitz, Sedwick, Ewing, Wang: "DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination." in: Science signaling, Vol. 3, Issue 146, pp. ra80, (2010) (PubMed).

Mistry, Gibson, Yun, Sarras, Tamblyn, McPherson: "Interplay between Np95 and Eme1 in the DNA damage response." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 321-5, (2008) (PubMed).

Target Details for UHRF1

Target: UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))

Alternative Name: UHRF1

Background: Full Gene Name: ubiquitin-like with PHD and ring finger domains 1
Synonyms: FLJ21925,ICBP90,MGC138707,Np95,RNF106,hNP95

Gene ID: 29128

NCBI Accession: NM_013282