UHRF1 antibody (AA 616-755)
Quick Overview for UHRF1 antibody (AA 616-755) (ABIN5542545)
Target
See all UHRF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 616-755
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Purpose
- UHRF1 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human UHRF1 (AA: 616-755) expressed in E. Coli.
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Isotype
- IgG2b
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anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 1-260) antibody
UHRF1 Reactivity: Human WB, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 694-793) antibodyUHRF1 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3A11 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 616-755) antibodyUHRF1 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 2A8C7 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 229-257) antibodyUHRF1 Reactivity: Human WB, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (N-Term) antibodyUHRF1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC, ICC, IP, ChIP Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 229-257) antibodyUHRF1 Reactivity: Human WB, IF, FACS Host: Rabbit Polyclonal RB21516 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibodyKO Validated UHRF1 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 596-628), (C-Term) antibodyUHRF1 Reactivity: Mouse WB Host: Rabbit Polyclonal RB51453 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (Internal Region) antibodyUHRF1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 592-626), (N-Term) antibodyUHRF1 Reactivity: Human WB Host: Rabbit Polyclonal RB51392 unconjugated
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
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Alternative Name
- UHRF1
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Background
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This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12.
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Molecular Weight
- 89.8 kDa
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Gene ID
- 29128
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UniProt
- Q96T88
Target
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