RAD21 antibody (AA 287-403)

Catalog No. ABIN5542652

This Mouse Monoclonal antibody specifically detects RAD21 in WB, ELISA, IHC, FACS and ICC. It exhibits reactivity toward Human, Rat and Monkey.

Quick Overview for RAD21 antibody (AA 287-403) (ABIN5542652)

Target: RAD21 (RAD21 Homolog (RAD21))

Reactivity: Human, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAD21 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 1B6D1

Product Details anti-RAD21 Antibody

Binding Specificity: AA 287-403

Purpose: RAD21 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RAD21 (AA: 287-403) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Alternative Name: RAD21

Background: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.

Molecular Weight: 71.7 kDa

Gene ID: 5885

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity