CBX5 antibody (AA 1-191)
Quick Overview for CBX5 antibody (AA 1-191) (ABIN5542711)
Target
See all CBX5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-191
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Purpose
- CBX5 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CBX5 (AA: 1-191) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CBX5 (Chromobox Homolog 5 (CBX5))
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Alternative Name
- CBX5
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Background
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This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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Molecular Weight
- 22.2 kDa
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Gene ID
- 23468
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UniProt
- P45973
Target
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