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Cytokeratin 18 antibody

This anti-Cytokeratin 18 antibody is a Rabbit Monoclonal antibody detecting Cytokeratin 18 in WB, FACS, IHC (p) and IF (cc). Suitable for Human.
Catalog No. ABIN5557298

Quick Overview for Cytokeratin 18 antibody (ABIN5557298)

Target

See all Cytokeratin 18 (KRT18) Antibodies
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity

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Human

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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This Cytokeratin 18 antibody is un-conjugated

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone

1F11
  • Cross-Reactivity

    Human

    Purification

    Purified by Protein A.

    Immunogen

    Recombinant human Cytokeratin 18 protein, full length.

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Target

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Alternative Name

    Cytokeratin 18

    Background

    Synonyms: K18, CK-18, CYK18, Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, Keratin-18, KRT18, PIG46

    Background: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

    Gene ID

    3875

    UniProt

    P05783

    Pathways

    Apoptosis, Caspase Cascade in Apoptosis
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