Recombinant TNFSF4 (Oxelumab Biosimilar) antibody

Catalog No. ABIN5564244

The Human Monoclonal anti-TNFSF4 (Oxelumab Biosimilar) antibody is suitable to detect TNFSF4 (Oxelumab Biosimilar) in samples from Human. It has been validated for FACS and Func.

Quick Overview for Recombinant TNFSF4 (Oxelumab Biosimilar) antibody (ABIN5564244)

Target: TNFSF4 (Oxelumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This TNFSF4 (Oxelumab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: R4930

Product Details anti-TNFSF4 (Oxelumab Biosimilar) Antibody

Specificity: Recognizes human OX40L.

Cross-Reactivity: Human

Purity: >95 % (SDS-PAGE)

Endotoxin Level: <0.001EU/μg

Immunogen: Recombinant human OX40L.

Isotype: IgG1

Application Details

Comment:

This antibody is a biosimilar generically called Oxelumab (CAS 1186098-83-8) and originally developed by Genentech. Oxelumab is a OX40 ligand blocker designed for the prevention of allergen-induced airway inflammation in adults with mild asthma. Potentially other application areas are transplantation and autoimmunity research or protection against inflammation-driven fibrosis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: In PBS.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 3 months after receipt when stored at +4°C.

Expiry Date: 12 months

Target Details for TNFSF4 (Oxelumab Biosimilar)

Target: TNFSF4 (Oxelumab Biosimilar)

Target Type: Biosimilar

Background: OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.

UniProt: P23510