Recombinant TNFSF4 (Oxelumab Biosimilar) antibody
The Human Monoclonal anti-TNFSF4 (Oxelumab Biosimilar) antibody has been validated for FACS and Func. It is suitable to detect TNFSF4 (Oxelumab Biosimilar) in samples from Human.
Catalog No. ABIN5564244
Quick Overview for Recombinant TNFSF4 (Oxelumab Biosimilar) antibody (ABIN5564244)
Target
TNFSF4 (Oxelumab Biosimilar)
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Human
Clonality
Monoclonal
Conjugate
This TNFSF4 (Oxelumab Biosimilar) antibody is un-conjugated
Application
Flow Cytometry (FACS), Functional Studies (Func)
Clone
R4930
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Specificity
- Recognizes human OX40L.
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Cross-Reactivity
- Human
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Purity
- >95 % (SDS-PAGE)
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Endotoxin Level
- <0.001EU/μg
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Immunogen
- Recombinant human OX40L.
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Isotype
- IgG1
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Comment
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This antibody is a biosimilar generically called Oxelumab (CAS 1186098-83-8) and originally developed by Genentech. Oxelumab is a OX40 ligand blocker designed for the prevention of allergen-induced airway inflammation in adults with mild asthma. Potentially other application areas are transplantation and autoimmunity research or protection against inflammation-driven fibrosis.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- In PBS.
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Preservative
- Without preservative
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 3 months after receipt when stored at +4°C. -
Expiry Date
- 12 months
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- TNFSF4 (Oxelumab Biosimilar)
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Target Type
- Biosimilar
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Background
- OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.
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UniProt
- P23510
Target
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