HDAC6 antibody (N-Term)

Catalog No. ABIN5596733

Supplier Product No.: 600-401-j40

This Rabbit Polyclonal antibody specifically detects HDAC6 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for HDAC6 antibody (N-Term) (ABIN5596733)

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HDAC6 Antibody

Binding Specificity: N-Term

Supplier Product No.: 600-401-j40

Supplier: Rockland

Purpose: HDAC6 (near N-terminus) Antibody

Cross-Reactivity (Details): A BLAST analysis was used to suggest cross-reactivity with monkey and human based on 100 % sequence homology.

Characteristics: Synonyms: rabbit anti-HDAC-6 antibody, HDAC6, HDAC 6, HD 6 antibody, histone deacetylase 6 antibody, Histone deacetylase-6, HD6 antibody, JM21

Purification: Anti-HDAC6 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterility: Sterile filtered

Immunogen:

Immunogen: HDAC6 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide near the N-terminus of human HDAC6.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-HDAC6 antibody has been tested by western blot and is useful for ELISA and immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~134 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1: 10,000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.17 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 30 % Glycerol

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Alternative Name: HDAC6

Background: Background: HDAC6 antibody is a cytoplasmic enzyme that regulates many cellular functions. In particular it has been implicated in cell migrations, degradation of misfolded proteins, tubulin and HSP90 deacylation. Anti-HDAC6 antibody is ideal for researchers interested in Stem Cell and Epigenetics and Nuclear Signaling research.

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling