ACTN1 antibody (AA 543-639)

Catalog No. ABIN559761

Cited in 2+ publications. The Mouse Monoclonal anti-ACTN1 antibody (Clone 3F1) (ABIN559761) specifically detects ACTN1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for ACTN1 antibody (AA 543-639) (ABIN559761)

Target: ACTN1 (Actinin, alpha 1 (ACTN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACTN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3F1

Product Details anti-ACTN1 Antibody

Binding Specificity: AA 543-639

Purpose: Mouse monoclonal antibody raised against a partial recombinant ACTN1.

Sequence: EIQGLTTAHE QFKATLPDAD KERLAILGIH NEVSKIVQTY HVNMAGTNPY TTITPQEING KWDHVRQLVP RRDQALTEEH ARQQHNERLR KQFGAQA

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ACTN1 (NP_001093, 543 a.a. ~ 639 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ACTN1 antibody (ABIN559761)

Sakane, Abdallah, Nakano, Honda, Ikeda, Nishikawa, Matsumoto, Matsushita, Kitamura, Sasaki: "Rab13 small G protein and junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development." in: The Journal of biological chemistry, Vol. 287, Issue 51, pp. 42455-68, (2012) (PubMed).

Quick, Skalli: "Alpha-actinin 1 and alpha-actinin 4: contrasting roles in the survival, motility, and RhoA signaling of astrocytoma cells." in: Experimental cell research, Vol. 316, Issue 7, pp. 1137-47, (2010) (PubMed).

Target Details for ACTN1

Target: ACTN1 (Actinin, alpha 1 (ACTN1))

Alternative Name: ACTN1

Background: Full Gene Name: actinin, alpha 1
Synonyms: FLJ40884

Gene ID: 87

NCBI Accession: NM_001102

Pathways: Cell-Cell Junction Organization