Activin A Receptor Type IB/ALK-4 antibody (AA 24-126)

Catalog No. ABIN559768

This Mouse Monoclonal antibody specifically detects Activin A Receptor Type IB/ALK-4 in WB, ELISA and PLA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Activin A Receptor Type IB/ALK-4 antibody (AA 24-126) (ABIN559768)

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Activin A Receptor Type IB/ALK-4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Proximity Ligation Assay (PLA)

Clone: 1C1

Product Details anti-Activin A Receptor Type IB/ALK-4 Antibody

Binding Specificity: AA 24-126

Purpose: Mouse monoclonal antibody raised against a partial recombinant ACVR1B.

Sequence: SGPRGVQALL CACTSCLQAN YTCETDGACM VSIFNLDGME HHVRTCIPKV ELVPAGKPFY CLSSEDLRNT HCCYTDYCNR IDLRVPSGHL KEPEHPSMWG PVE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ACVR1B (AAH00254, 24 a.a. ~ 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Activin A Receptor Type IB/ALK-4 antibody (ABIN559768)

Zhu, Xu, Cuascut, Hall, Oxford: "Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 50, pp. 13770-80, (2007) (PubMed).

Target Details for Activin A Receptor Type IB/ALK-4

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Alternative Name: ACVR1B

Background: Full Gene Name: activin A receptor, type IB
Synonyms: ACTRIB,ACVRLK4,ALK4,SKR2

Gene ID: 91