FASL antibody (AA 172-281)

Catalog No. ABIN559911

Cited in 1 publication. The Mouse Monoclonal anti-FASL antibody (Clone 3F3) (ABIN559911) specifically detects FASL in ELISA. The antibody is reactive with Human samples.

Quick Overview for FASL antibody (AA 172-281) (ABIN559911)

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FASL antibody is un-conjugated

Application: ELISA

Clone: 3F3

Product Details anti-FASL Antibody

Binding Specificity: AA 172-281

Purpose: Mouse monoclonal antibody raised against a partial recombinant FASLG.

Sequence: SGVKYKKGGL VINETGLYFV YSKVYFRGQS CNNLPLSHKV YMRNSKYPQD LVMMEGKMMS YCTTGQMWAR SSYLGAVFNL TSADHLYVNV SELSLVNFEE SQTFFGLYKL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FASLG (AAH17502.1, 172 a.a. ~ 281 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FASL antibody (ABIN559911)

Bach, Szabo, Dighe, Ashkenazi, Aguet, Murphy, Schreiber: "Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets." in: Science (New York, N.Y.), Vol. 270, Issue 5239, pp. 1215-8, (1996) (PubMed).

Target Details for FASL

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Alternative Name: FASLG

Background: Full Gene Name: Fas ligand (TNF superfamily, member 6)
Synonyms: APT1LG1,CD178,CD95L,FASL,TNFSF6

Gene ID: 356

NCBI Accession: NM_000639

Pathways: Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity