CBR1 antibody (AA 1-277)

Catalog No. ABIN560201

The Mouse Monoclonal anti-CBR1 antibody has been validated for WB and ELISA. It is suitable to detect CBR1 in samples from Human. There are 2+ publications available.

Quick Overview for CBR1 antibody (AA 1-277) (ABIN560201)

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 4G11-1C7

Product Details anti-CBR1 Antibody

Binding Specificity: AA 1-277

Purpose: Mouse monoclonal antibody raised against a full length recombinant CBR1.

Sequence: MSSGIHVALV TGGNKGIGLA IVRDLCRLFS GDVVLTARDV TRGQAAVQQL QAEGLSPRFH QLDIDDLQSI RALRDFLRKE YGGLDVLVNN AGIAFKVADP TPFHIQAEVT MKTNFFGTRD VCTELLPLIK PQGRVVNVSS IMSVRALKSC SPELQQKFRS ETITEEELVG LMNKFVEDTK KGVHQKEGWP SSAYGVTKIG VTVLSRIHAR KLSEQRKGDK ILLNACCPGW VRTDMAGPKA TKSPEEGAET PVYLALLPPD AEGPHGQFVS EKRVEQW

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CBR1 (AAH02511.1, 1 a.a. ~ 277 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CBR1 antibody (ABIN560201)

Rashid, Lee, Tak, Lee, Choi, Lee, Kim, Youn, Kang, Ha, Kim: "Carbonyl reductase 1 protects pancreatic β-cells against oxidative stress-induced apoptosis in glucotoxicity and glucolipotoxicity." in: Free radical biology & medicine, Vol. 49, Issue 10, pp. 1522-33, (2010) (PubMed).

Bains, Karkling, Grigliatti, Reid, Riggs: "Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 5, pp. 1107-14, (2009) (PubMed).

Target Details for CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Alternative Name: CBR1

Background: Full Gene Name: carbonyl reductase 1
Synonyms: CBR,SDR21C1,hCBR1

Gene ID: 873