CTNS antibody (AA 1-100)

Catalog No. ABIN560527

This Mouse Monoclonal antibody specifically detects CTNS in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for CTNS antibody (AA 1-100) (ABIN560527)

Target: CTNS (Cystinosis, Nephropathic (CTNS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTNS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 5G6

Product Details anti-CTNS Antibody

Binding Specificity: AA 1-100

Purpose: Mouse monoclonal antibody raised against a partial recombinant CTNS.

Sequence: MIRNWLTIFI LFPLKLVEKC ESSVSLTVPP VVKLENGSST NVSLTLRPPL NATLVITFEI TFRSKNITIL ELPDEVVVPP GVTNSSFQVT SQNVGQLTVY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CTNS (NP_004928, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CTNS antibody (ABIN560527)

McEvoy, Sumayao, Slattery, McMorrow, Newsholme: "Cystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels." in: The Journal of physiology, Vol. 593, Issue 23, pp. 5167-82, (2015) (PubMed).

Bellomo, Corallini, Pastore, Palma, Laurenzi, Emma, Taranta: "Modulation of CTNS gene expression by intracellular thiols." in: Free radical biology & medicine, Vol. 48, Issue 7, pp. 865-72, (2010) (PubMed).

Target Details for CTNS

Target: CTNS (Cystinosis, Nephropathic (CTNS))

Alternative Name: CTNS

Background: Full Gene Name: cystinosis, nephropathic
Synonyms: CTNS-LSB,PQLC4

Gene ID: 1497

NCBI Accession: NM_004937