CYP24A1 antibody (AA 415-514)

Catalog No. ABIN560551

This Mouse Polyclonal antibody specifically detects CYP24A1 in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for CYP24A1 antibody (AA 415-514) (ABIN560551)

Target: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This CYP24A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CYP24A1 Antibody

Binding Specificity: AA 415-514

Purpose: Mouse polyclonal antibody raised against a partial recombinant CYP24A1.

Sequence: LMLNTQVLGS SEDNFEDSSQ FRPERWLQEK EKINPFAHLP FGVGKRMCIG RRLAELQLHL ALCWIVRKYD IQATDNEPVE MLHSGTLVPS RELPIAFCQR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CYP24A1 (NP_000773, 415 a.a. ~ 514 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CYP24A1 antibody (ABIN560551)

Kotani, Tanabe, Mizukami, Amagaya, Inoue: "A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers." in: Biological & pharmaceutical bulletin, Vol. 35, Issue 1, pp. 1-9, (2012) (PubMed).

Peng, Jhaveri, Hussain-Hakimjee, Mehta: "Overexpression of ER and VDR is not sufficient to make ER-negative MDA-MB231 breast cancer cells responsive to 1alpha-hydroxyvitamin D5." in: Carcinogenesis, Vol. 28, Issue 5, pp. 1000-7, (2007) (PubMed).

Target Details for CYP24A1

Target: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Alternative Name: CYP24A1

Background: Full Gene Name: cytochrome P450, family 24, subfamily A, polypeptide 1
Synonyms: CP24,CYP24,MGC126273,MGC126274,P450-CC24

Gene ID: 1591

NCBI Accession: NM_000782

Pathways: Metabolism of Steroid Hormones and Vitamin D