Dystroglycan antibody (AA 31-140)

Catalog No. ABIN560555

The Mouse Monoclonal anti-Dystroglycan antibody has been validated for WB and ELISA. It is suitable to detect Dystroglycan in samples from Human. There is 1 publication available.

Quick Overview for Dystroglycan antibody (AA 31-140) (ABIN560555)

Target: Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Dystroglycan antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2A3

Product Details anti-Dystroglycan Antibody

Binding Specificity: AA 31-140

Purpose: Mouse monoclonal antibody raised against a partial recombinant DAG1.

Sequence: WPSEPSEAVR DWENQLEASM HSVLSDLHEA VPTVVGIPDG TAVVGRSFRV TIPTDLIASS GDIIKVSAAG KEALPSWLHW DSQSHTLEGL PLDTDKGVHY ISVSATRLGA

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DAG1 (AAH12740, 31 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Dystroglycan antibody (ABIN560555)

Hesse, Johansson, Mattsson, Bremell, Andreasson, Halim, Anckarsäter, Blennow, Anckarsäter, Zetterberg, Larson, Hagberg, Grahn: "The N-terminal domain of ?-dystroglycan, released as a 38 kDa protein, is increased in cerebrospinal fluid in patients with Lyme neuroborreliosis." in: Biochemical and biophysical research communications, Vol. 412, Issue 3, pp. 494-9, (2011) (PubMed).

Target Details for Dystroglycan

Target: Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

Alternative Name: DAG1

Background: Full Gene Name: dystroglycan 1 (dystrophin-associated glycoprotein 1)
Synonyms: 156DAG,A3a,AGRNR,DAG

Gene ID: 1605

Pathways: Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus