DDX6 antibody (AA 1-483)

Catalog No. ABIN560590

This Mouse Monoclonal antibody specifically detects DDX6 in WB, ELISA, IHC (p) and RNAi. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for DDX6 antibody (AA 1-483) (ABIN560590)

Target: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DDX6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Clone: 3D2

Product Details anti-DDX6 Antibody

Binding Specificity: AA 1-483

Purpose: Mouse monoclonal antibody raised against a full length recombinant DDX6.

Sequence: MSTARTENPV IMGLSSQNGQ LRGPVKPTGG PGGGGTQTQQ QMNQLKNTNT INNGTQQQAQ SMTTTIKPGD DWKKTLKLPP KDLRIKTSDV TSTKGNEFED YCLKRELLMG IFEMGWEKPS PIQEESIPIA LSGRDILARA KNGTGKSGAY LIPLLERLDL KKDNIQAMVI VPTRELALQV SQICIQVSKH MGGAKVMATT GGTNLRDDIM RLDDTVHVVI ATPGRILDLI KKGVAKVDHV QMIVLDEADK LLSQDFVQIM EDIILTLPKN RQILLYSATF PLSVQKFMNS HLQKPYEINL MEELTLKGVT QYYAYVTERQ KVHCLNTLFS RLQINQSIIF CNSSQRVELL AKKISQLGYS CFYIHAKMRQ EHRNRVFHDF RNGLCRNLVC TDLFTRGIDI QAVNVVINFD FPKLAETYLH RIGRSGRFGH LGLAINLITY DDRFNLKSIE EQLGTEIKPI PSNIDKSLYV AEYHSEPVED EKP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DDX6 (AAH65007, 1 a.a. ~ 483 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-DDX6 antibody (ABIN560590)

Kawahara, Yokota, Fujita: "DDX6 localizes to nuage structures and the annulus of mammalian spermatogenic cells." in: Histochemistry and cell biology, Vol. 141, Issue 1, pp. 111-21, (2014) (PubMed).

Yu, Lujan, Jackson, Emerman, Linial: "The DEAD-box RNA helicase DDX6 is required for efficient encapsidation of a retroviral genome." in: PLoS pathogens, Vol. 7, Issue 10, pp. e1002303, (2011) (PubMed).

Broytman, Westmark, Gurel, Malter: "Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines." in: Neurobiology of aging, Vol. 30, Issue 12, pp. 1962-74, (2009) (PubMed).

Target Details for DDX6

Target: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Alternative Name: DDX6

Background: Full Gene Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
Synonyms: FLJ36338,HLR2,P54,RCK

Gene ID: 1656

Pathways: Ribonucleoprotein Complex Subunit Organization