ETV6 antibody (AA 1-452)

Catalog No. ABIN560810

The Mouse Monoclonal anti-ETV6 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect ETV6 in samples from Human. There are 2+ publications available.

Quick Overview for ETV6 antibody (AA 1-452) (ABIN560810)

Target: ETV6 (Ets Variant 6 (ETV6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ETV6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3B10

Product Details anti-ETV6 Antibody

Binding Specificity: AA 1-452

Purpose: Mouse monoclonal antibody raised against a full length recombinant ETV6.

Sequence: MSETPAQCSI KQERISYTPP ESPVPSYASS TPLHVPVPRA LRMEEDSIRL PAHLRLQPIY WSRDDVAQWL KWAENEFSLR PIDSNTFEMN GKALLLLTKE DFRYRSPHSG DVLYELLQHI LKQRKPRILF SPFFHPGNSI HTQPEVILHQ NHEEDNCVQR TPRPSVDNVH HNPPTIELLH RSRSPITTNH RPSPDPEQRP LRSPLDNMIR RLSPAERAQG PRPHQENNHQ ESYPLSVSPM ENNHCPASSE SHPKPSSPRQ ESTRVIQLMP SPIMHPLILN PRHSVDFKQS RLSEDGLHRE GKPINLSHRE DLAYMNHIMV SVSPPEEHAM PIGRIADCRL LWDYVYQLLS DSRYENFIRW EDKESKIFRI VDPNGLARLW GNHKNRTNMT YEKMSRALRH YYKLNIIRKE PGQRLLFRFM KTPDEIMSGR TDRLEHLESQ ELDEQIYQED EC

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ETV6 (AAH43399, 1 a.a. ~ 452 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ETV6 antibody (ABIN560810)

Meester-Smoor, Janssen, ter Haar, van Wely, Aarnoudse, van Oord, van Tilburg, Zwarthoff: "The ETS family member TEL binds to nuclear receptors RAR and RXR and represses gene activation." in: PLoS ONE, Vol. 6, Issue 9, pp. e23620, (2011) (PubMed).

Van Vlierberghe, Ambesi-Impiombato, Perez-Garcia, Haydu, Rigo, Hadler, Tosello, Della Gatta, Paietta, Racevskis, Wiernik, Luger, Rowe, Rue, Ferrando: "ETV6 mutations in early immature human T cell leukemias." in: The Journal of experimental medicine, Vol. 208, Issue 13, pp. 2571-9, (2011) (PubMed).

Target Details for ETV6

Target: ETV6 (Ets Variant 6 (ETV6))

Alternative Name: ETV6

Background: Full Gene Name: ets variant 6
Synonyms: TEL,TEL/ABL

Gene ID: 2120