RbAp46/48 antibody
Quick Overview for RbAp46/48 antibody (ABIN5608738)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Cross-Reactivity
- Human
-
Purification
- Ascites fluid from mouse containing 0.05% azide
-
Immunogen
- Monoclonal antibody raised in mouse against the full length human RbAp48 protein (Retinoblastoma-binding protein p48) fused to GST. The antibody recognizes both RbAp48 and RbAp46
-
Isotype
- IgG2b
-
-
anti-RbAp46/48 antibody
Reactivity: Human WB, ChIP Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
-
WB 1:300-5000
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Ascites fluid with 0.05 % sodium azide.
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C for 12 months.
-
Expiry Date
- 12 months
-
-
- RbAp46/48
-
Alternative Name
- RbAp 46/48
-
Background
-
Synonyms: Histone-binding protein RBBP4, RBBP4, p48, RBBP-4, RBAP48
Background: Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.
-
Gene ID
- 5928
-
UniProt
- Q09028
Target
-
