TNFRSF13C antibody (AA 1-78)
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- Target See all TNFRSF13C Antibodies
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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Binding Specificity
- AA 1-78
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNFRSF13C antibody is un-conjugated
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Application
- Flow Cytometry (FACS), ELISA
- Purpose
- CD268 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD268 (AA: 1-78) expressed in E. Coli.
- Clone
- 5A9B10
- Isotype
- IgG2b
- Top Product
- Discover our top product TNFRSF13C Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
- Alternative Name
- CD268 (TNFRSF13C Products)
- Background
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Description: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Aliases: TNFRSF13C, BAFFR, CVID4, BAFF-R, BROMIX, prolixin
- Molecular Weight
- 18.9kDa
- Gene ID
- 115650
- HGNC
- 115650
- UniProt
- Q96RJ3
- Pathways
- NF-kappaB Signaling
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