TNFRSF13C antibody (Tumor Necrosis Factor Receptor Superfamily, Member 13C) (AA 1-78)

Details for Product anti-TNFRSF13C Antibody No. ABIN5611148
Antigen
Epitope
AA 1-78
16
12
10
6
6
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
143
78
42
3
2
2
2
2
1
Host
Mouse
109
51
23
Clonality (Clone)
Monoclonal ()
Conjugate
This TNFRSF13C antibody is un-conjugated
20
9
8
6
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
ELISA, Flow Cytometry (FACS), Western Blotting (WB)
92
66
50
28
24
13
10
8
4
4
2
2
1
Options
Immunogen Purified recombinant fragment of human CD268 (AA extra 1-78) expressed in E. Coli.
Clone 5A9B6
Isotype IgG2b
Antigen
Alternative Name CD268 (TNFRSF13C Antibody Abstract)
Background B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Molecular Weight 18.9kDa
HGNC 115650
Pathways NF-kappaB Signaling
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N:A, FCM: 1:200 - 1:400, IHC: N:A
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-78) antibody (ABIN5611148) Western blot analysis using CD268 mouse mAb against C6 (1) cell lysate.
Image no. 2 for anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-78) antibody (ABIN5611148) Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen ...
Image no. 3 for anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-78) antibody (ABIN5611148) Western blot analysis using CD268 mAb against HEK293 (1) and CD268 (AA: extra 1-78)-h...
Image no. 4 for anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-78) antibody (ABIN5611148) Western blot analysis using CD268 mAb against human CD268 (AA: extra 1-78) recombinan...
Image no. 5 for anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-78) antibody (ABIN5611148) Flow cytometric analysis of Raji cells using CD268 mouse mAb (green) and negative con...