TNFRSF13C antibody (AA 1-78)

Catalog No. ABIN5611147

The Mouse Monoclonal anti-TNFRSF13C antibody (Clone 5A9B10) (ABIN5611147) specifically detects TNFRSF13C in FACS and ELISA. The antibody is reactive with Human samples.

Quick Overview for TNFRSF13C antibody (AA 1-78) (ABIN5611147)

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF13C antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: 5A9B10

Product Details anti-TNFRSF13C Antibody

Binding Specificity: AA 1-78

Purpose: CD268 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD268 (AA: 1-78) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TNFRSF13C

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Alternative Name: CD268

Background: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Molecular Weight: 18.9 kDa

UniProt: Q96RJ3

Pathways: NF-kappaB Signaling