PRKAA2 antibody (AA 453-552)
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- Target See all PRKAA2 Antibodies
- PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
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Binding Specificity
- AA 453-552
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PRKAA2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purpose
- PRKAA2 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PRKAA2 (AA: 453-552) expressed in E. Coli.
- Clone
- 8E11H5
- Isotype
- IgG1
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anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (Center) antibody
PRKAA2 Reactivity: Human, Mouse WB, IF, IHC (p), IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 453-552) antibodyPRKAA2 Reactivity: Human WB, ELISA, IF, RNAi, PLA Host: Mouse Monoclonal 1G8 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 351-450) antibodyPRKAA2 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 1-552) antibodyPRKAA2 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 350-400), (Catalytic Subunit alpha) antibodyPRKAA2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 265-295) antibodyPRKAA2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB3173 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 265-294) antibodyPRKAA2 Reactivity: Human WB Host: Rabbit Polyclonal RB15728 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 145-173), (Thr172) antibodyPRKAA2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB25835 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (Internal Region) antibodyVerified PRKAA2 Reactivity: Human, Mouse, Rat WB, ELISA Host: Goat Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 343-552) antibodyPRKAA2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
- Alternative Name
- PRKAA2 (PRKAA2 Products)
- Background
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Description: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Aliases: AMPK, AMPK2, PRKAA, AMPKa2
- Molecular Weight
- 62.3kDa
- Gene ID
- 5563
- HGNC
- 5563
- UniProt
- P54646
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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