PRKAB2 antibody (AA 1-120)
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- Target See all PRKAB2 Antibodies
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
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Binding Specificity
- AA 1-120
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PRKAB2 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- PRKAB2 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PRKAB2 (AA: 1-120) expressed in E. Coli.
- Clone
- 7A8C3
- Isotype
- IgG2b
- Top Product
- Discover our top product PRKAB2 Primary Antibody
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anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-120) antibody
PRKAB2 Reactivity: Human IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 8F5B2 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2G9 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 56-89), (N-Term) antibodyPRKAB2 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 3-33), (N-Term) antibodyPRKAB2 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB3183 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-110) antibodyPRKAB2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 17-260) antibodyPRKAB2 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 17-260) antibodyPRKAB2 Reactivity: Human WB, IHC, IF/ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) antibodyPRKAB2 Reactivity: Human, Mouse, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
- Alternative Name
- PRKAB2 (PRKAB2 Products)
- Background
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The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
- 30.3kDa
- Gene ID
- 5565
- HGNC
- 5565
- UniProt
- O43741
- Pathways
- AMPK Signaling, Warburg Effect
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