BAG1 antibody (AA 219-346)
Quick Overview for BAG1 antibody (AA 219-346) (ABIN5611249)
Target
See all BAG1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 219-346
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Purpose
- BAG1 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human BAG1 (AA: 219-346) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- BAG1 (BCL2-Associated Athanogene (BAG1))
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Alternative Name
- BAG1
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Background
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The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
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Molecular Weight
- 38.8 kDa
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Gene ID
- 573
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UniProt
- Q99933
Target
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