BCL2L10 antibody (AA 31-186)

Catalog No. ABIN5611303

This anti-BCL2L10 antibody is a Mouse Monoclonal antibody detecting BCL2L10 in ELISA and FACS. Suitable for Human.

Quick Overview for BCL2L10 antibody (AA 31-186) (ABIN5611303)

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL2L10 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 8A11G12

Product Details anti-BCL2L10 Antibody

Binding Specificity: AA 31-186

Purpose: BCL2L10 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human BCL2L10 (AA: 31-186) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for BCL2L10

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Alternative Name: BCL2L10

Background: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Molecular Weight: 22 kDa

UniProt: Q9HD36

Pathways: Positive Regulation of Endopeptidase Activity