CD11c antibody (AA 102-279)

Catalog No. ABIN5611306

Product Details anti-CD11c Antibody

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Binding Specificity: AA 102-279

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD11c antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Purpose: CD11C Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD11C (AA: 102-279) expressed in E. Coli.

Clone: 6G2D1

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CD11c

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Alternative Name: CD11C (ITGAX Products)

Background:

Description: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

Aliases: ITGAX, SLEB6

Molecular Weight: 127.8kDa

Gene ID: 3687

HGNC: 3687

UniProt: P20702

Pathways: Complement System, Activated T Cell Proliferation, Integrin Complex