GLRB antibody (AA 23-160)

Catalog No. ABIN5611340

This Mouse Monoclonal antibody specifically detects GLRB in ELISA, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for GLRB antibody (AA 23-160) (ABIN5611340)

Target: GLRB (Glycine Receptor, beta (GLRB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLRB antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 3B8A8

Product Details anti-GLRB Antibody

Binding Specificity: AA 23-160

Purpose: GLRB Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human GLRB (AA: 23-160) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for GLRB

Target: GLRB (Glycine Receptor, beta (GLRB))

Alternative Name: GLRB

Background: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Molecular Weight: 56.1 kDa

Gene ID: 2743

UniProt: P48167