Vitamin D-Binding Protein antibody

Catalog No. ABIN5611471

The Rabbit Polyclonal anti-Vitamin D-Binding Protein antibody has been validated for IHC (p) and EIA. It is suitable to detect Vitamin D-Binding Protein in samples from Human.

Quick Overview for Vitamin D-Binding Protein antibody (ABIN5611471)

Target: Vitamin D-Binding Protein (GC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitamin D-Binding Protein antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Vitamin D-Binding Protein Antibody

Specificity: Recognizes Vitamin D binding protein (VDBP), the major carrier protein of vitamin D that also transports components such as fatty acids and endotoxins and has an important role in the actin scavenging system. VDBP is a 52-58 kDa plasma protein synthesized mainly by hepatocytes. Polymorphisms in the gene give rise to three major electrophoretic variants, Gc1, Gc1s and Gc1f that differ by amino acid substitutions as well as glycosylations. The physiological significance of these phenotypes has yet to be determined.

Purification: Protein G Chromatography

Immunogen: Native human vitamin D binding protein Genename: GC

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5,0 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Vitamin D-Binding Protein

Target: Vitamin D-Binding Protein (GC)

Alternative Name: Vitamin D-Binding Protein

Background: Synonyms: DBP, Gc-globulin, Group-specific component, VDB

Gene ID: 2638

NCBI Accession: NP_000574

UniProt: P02774

Pathways: Metabolism of Steroid Hormones and Vitamin D, Monocarboxylic Acid Catabolic Process