HFE antibody (AA 115-205)

Catalog No. ABIN561252

This anti-HFE antibody is a Mouse Monoclonal antibody detecting HFE in WB, ELISA and IF. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for HFE antibody (AA 115-205) (ABIN561252)

Target: HFE (Hemochromatosis (HFE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HFE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 1G12

Product Details anti-HFE Antibody

Binding Specificity: AA 115-205

Purpose: Mouse monoclonal antibody raised against a partial recombinant HFE.

Sequence: SHTLQVILGC EMQEDNSTEG YWKYGYDGQD HLEFCPDTLD WRAAEPRAWP TKLEWERHKI RARQNRAYLE RDCPAQLQQL LELGRGVLDQ Q

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HFE (NP_000401, 115 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-HFE antibody (ABIN561252)

Lenarduzzi, Hui, Yue, Ito, Shi, Williams, Bruce, Sakemura-Nakatsugawa, Xu, Schimmer, Liu: "Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer." in: PLoS ONE, Vol. 8, Issue 8, pp. e74075, (2013) (PubMed).

Target Details for HFE

Target: HFE (Hemochromatosis (HFE))

Alternative Name: HFE

Background: Full Gene Name: hemochromatosis
Synonyms: HFE1,HH,HLA-H,MGC103790,dJ221C16.10.1

Gene ID: 3077

NCBI Accession: NM_000410

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process