Macrophage Mannose Receptor 1 antibody (AA 22-130)

Catalog No. ABIN561847

This Mouse Monoclonal antibody specifically detects Macrophage Mannose Receptor 1 in WB, ELISA and IHC (p). It exhibits reactivity toward Human. It has been mentioned in 9+ publications

Quick Overview for Macrophage Mannose Receptor 1 antibody (AA 22-130) (ABIN561847)

Target: Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Macrophage Mannose Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5C11

Product Details anti-Macrophage Mannose Receptor 1 Antibody

Binding Specificity: AA 22-130

Purpose: Mouse monoclonal antibody raised against a partial recombinant MRC1.

Sequence: TRQFLIYNED HKRCVDAVSP SAVQTAACNQ DAESQKFRWV SESQIMSVAF KLCLGVPSKT DWVAITLYAC DSKSEFQKWE CKNDTLLGIK GEDLFFNYGN RQEKNIMLY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MRC1 (NP_002429, 22 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Macrophage Mannose Receptor 1 antibody (ABIN561847)

Olmes, Büttner-Herold, Ferrazzi, Distel, Amann, Daniel: "CD163+ M2c-like macrophages predominate in renal biopsies from patients with lupus nephritis." in: Arthritis research & therapy, Vol. 18, pp. 90, (2016) (PubMed).

Weber, Moebius, Büttner-Herold, Amann, Preidl, Neukam, Wehrhan: "Macrophage polarisation changes within the time between diagnostic biopsy and tumour resection in oral squamous cell carcinomas--an immunohistochemical study." in: British journal of cancer, Vol. 113, Issue 3, pp. 510-9, (2015) (PubMed).

Weber, Büttner-Herold, Hyckel, Moebius, Distel, Ries, Amann, Neukam, Wehrhan: "Small oral squamous cell carcinomas with nodal lymphogenic metastasis show increased infiltration of M2 polarized macrophages--an immunohistochemical analysis." in: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, Vol. 42, Issue 7, pp. 1087-94, (2014) (PubMed).

Canna, Costa-Reis, Bernal, Chu, Sullivan, Paessler, Behrens: "Brief report: alternative activation of laser-captured murine hemophagocytes." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 66, Issue 6, pp. 1666-71, (2014) (PubMed).

Holder, McGary, Johnson, Zheng, John, Sugimoto, Kuroda, Kim: "Expression of the mannose receptor CD206 in HIV and SIV encephalitis: a phenotypic switch of brain perivascular macrophages with virus infection." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 9, Issue 5, pp. 716-26, (2014) (PubMed).

Wehrhan, Büttner-Herold, Hyckel, Moebius, Preidl, Distel, Ries, Amann, Schmitt, Neukam, Weber: "Increased malignancy of oral squamous cell carcinomas (oscc) is associated with macrophage polarization in regional lymph nodes - an immunohistochemical study." in: BMC cancer, Vol. 14, pp. 522, (2014) (PubMed).

Itano, Graus, Pehlke, Wester, Liu, Lidke, Thompson, Jacobson, Neumann: "Super-resolution imaging of C-type lectin spatial rearrangement within the dendritic cell plasma membrane at fungal microbe contact sites." in: Frontiers in physics, Vol. 2, (2014) (PubMed).

Zhuang, Zhu, Wang, Zhou, Quan, Shen: "Xanthogranulomatous cholecystitis: a clinicopathological study of its association with gallbladder carcinoma." in: Journal of digestive diseases, Vol. 14, Issue 1, pp. 45-50, (2013) (PubMed).

Hirata, Tabata, Kurobe, Motoki, Akaike, Nishio, Higashida, Mikasa, Nakaya, Takanashi, Igarashi, Kitagawa, Sata: "Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue." in: Journal of the American College of Cardiology, Vol. 58, Issue 3, pp. 248-55, (2011) (PubMed).

Target Details for Macrophage Mannose Receptor 1

Target: Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))

Alternative Name: MRC1

Background: Full Gene Name: mannose receptor, C type 1
Synonyms: CD206,CLEC13D,MMR

Gene ID: 4360

NCBI Accession: NM_002438