PHKA1 antibody (AA 631-730)

Catalog No. ABIN562210

This Mouse Polyclonal antibody specifically detects PHKA1 in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for PHKA1 antibody (AA 631-730) (ABIN562210)

Target: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PHKA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PHKA1 Antibody

Binding Specificity: AA 631-730

Purpose: Mouse polyclonal antibody raised against a partial recombinant PHKA1.

Sequence: DYDDNYDYLE SGNWMNDYDS TSHARCGDEV ARYLDHLLAH TAPHPKLAPT SQKGGLDRFQ AAVQTTCDLM SLVTKAKELH VQNVHMYLPT KLFQASRPSF

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PHKA1 (NP_002628, 631 a.a. ~ 730 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PHKA1 antibody (ABIN562210)

Benzina, Pitaval, Lemercier, Lustremant, Frouin, Wu, Papine, Soussaline, Romeo, Gidrol: "A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation." in: Cellular and molecular life sciences : CMLS, (2015) (PubMed).

Quinlan, Seto, Turner, Vandebrouck, Floetenmeyer, Macarthur, Raftery, Lek, Yang, Parton, Cooney, North: "Alpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle." in: Human molecular genetics, Vol. 19, Issue 7, pp. 1335-46, (2010) (PubMed).

Target Details for PHKA1

Target: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Alternative Name: PHKA1

Background: Full Gene Name: phosphorylase kinase, alpha 1 (muscle)
Synonyms: MGC132604,PHKA

Gene ID: 5255

NCBI Accession: NM_002637

Pathways: Cellular Glucan Metabolic Process