RABGGTB antibody (AA 1-331)

Catalog No. ABIN562561

This Mouse Monoclonal antibody specifically detects RABGGTB in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for RABGGTB antibody (AA 1-331) (ABIN562561)

Target: RABGGTB (Rab Geranylgeranyltransferase, beta Subunit (RABGGTB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RABGGTB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1C2

Product Details anti-RABGGTB Antibody

Binding Specificity: AA 1-331

Purpose: Mouse monoclonal antibody raised against a full length recombinant RABGGTB.

Sequence: MGTPQKDVII KSDAPDTLLL EKHADYIASY GSKKDDYEYC MSEYLRMSGI YWGLTVMDLM GQLHRMNREE ILAFIKSCQH ECGGISASIG HDPHLLYTLS AVQILTLYDS INVIDVNKVV EYVKGLQKED GSFAGDIWGE IDTRFSFCAV ATLALLGKLD AINVEKAIEF VLSCMNFDGG FGCRPGSESH AGQIYCCTGF LAITSQLHQV NSDLLGWWLC ERQLPSGGLN GRPEKLPDVC YSWWVLASLK IIGRLHWIDR EKLRNFILAC QDEETGGFAD RPGDMVDPFH TLFGIAGLSL LGEEQIKPVN PVFCMPEEVL QRVNVQPELV S

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RABGGTB (AAH20790, 1 a.a. ~ 331 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RABGGTB antibody (ABIN562561)

Ageberg, Rydström, Lindén, Linderoth, Jerkeman, Drott: "Inhibition of geranylgeranylation mediates sensitivity to CHOP-induced cell death of DLBCL cell lines." in: Experimental cell research, Vol. 317, Issue 8, pp. 1179-91, (2011) (PubMed).

Hooper, Gaggioli, Sahai: "A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion." in: British journal of cancer, Vol. 102, Issue 2, pp. 392-402, (2010) (PubMed).

Target Details for RABGGTB

Target: RABGGTB (Rab Geranylgeranyltransferase, beta Subunit (RABGGTB))

Alternative Name: RABGGTB

Background: Full Gene Name: Rab geranylgeranyltransferase, beta subunit
Synonyms: GGTB

Gene ID: 5876