SRSF3 antibody (AA 1-85)

Catalog No. ABIN562839

This anti-SRSF3 antibody is a Mouse Monoclonal antibody detecting SRSF3 in WB, ELISA and IF. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for SRSF3 antibody (AA 1-85) (ABIN562839)

Target: SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SRSF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2D2

Product Details anti-SRSF3 Antibody

Binding Specificity: AA 1-85

Purpose: Mouse monoclonal antibody raised against a partial recombinant SFRS3.

Sequence: MHRDSCPLDC KVYVGNLGNN GNKTELERAF GYYGPLRSVW VARNPPGFAF VEFEDPRDAA DAVRELDGRT LCGCRVRVEL SNGEK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SFRS3 (NP_003008, 1 a.a. ~ 85 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SRSF3 antibody (ABIN562839)

Moura-Alves, Neves-Costa, Raquel, Pacheco, DAlmeida, Rodrigues, Cadima-Couto, Chora, Oliveira, Gama-Carvalho, Hacohen, Moita: "An shRNA-based screen of splicing regulators identifies SFRS3 as a negative regulator of IL-1? secretion." in: PLoS ONE, Vol. 6, Issue 5, pp. e19829, (2011) (PubMed).

Garbes, Riessland, Hölker, Heller, Hauke, Tränkle, Coras, Blümcke, Hahnen, Wirth: "LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate." in: Human molecular genetics, Vol. 18, Issue 19, pp. 3645-58, (2009) (PubMed).

Target Details for SRSF3

Target: SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

Alternative Name: SFRS3

Background: Full Gene Name: splicing factor, arginine/serine-rich 3
Synonyms: SRp20

Gene ID: 6428

NCBI Accession: NM_003017