Mps1 antibody (AA 1-176)

Catalog No. ABIN563279

The Mouse Monoclonal anti-Mps1 antibody has been validated for WB and ELISA. It is suitable to detect Mps1 in samples from Human. There is 1 publication available.

Quick Overview for Mps1 antibody (AA 1-176) (ABIN563279)

Target: Mps1 (TTK)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Mps1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3G7

Product Details anti-Mps1 Antibody

Binding Specificity: AA 1-176

Purpose: Mouse monoclonal antibody raised against a partial recombinant TTK.

Sequence: MESEDLSGRE LTIDSIMNKV RDIKNKFKNE DLTDELSLNK ISADTTDNSG TVNQIMMMAN NPEDWLSLLL KLEKNSVPLS DALLNKLIGR YSQAIEALPP DKYGQNESFA RIQVRFAELK AIQEPDDARD YFQMARANCK KFAFVHISFA QFELSQGNVK KSKQLLQKAV ERGAVP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TTK (AAH00633, 1 a.a. ~ 176 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Mps1 antibody (ABIN563279)

Niittymäki, Gylfe, Laine, Laakso, Lehtonen, Kondelin, Tolvanen, Nousiainen, Pouwels, Järvinen, Nuorva, Mecklin, Mäkinen, Ristimäki, Ørntoft, Hautaniemi, Karhu, Kallio, Aaltonen: "High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint." in: Carcinogenesis, Vol. 32, Issue 3, pp. 305-11, (2011) (PubMed).

Target Details for Mps1

Target: Mps1 (TTK)

Alternative Name: TTK

Background: Full Gene Name: TTK protein kinase
Synonyms: ESK,FLJ38280,MPS1,MPS1L1,PYT

Gene ID: 7272