RUVBL1 antibody (AA 1-456)

Catalog No. ABIN563710

This Mouse Monoclonal antibody specifically detects RUVBL1 in WB, ELISA, IF and PLA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for RUVBL1 antibody (AA 1-456) (ABIN563710)

Target: RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUVBL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Proximity Ligation Assay (PLA)

Clone: 3G4-1F8

Product Details anti-RUVBL1 Antibody

Binding Specificity: AA 1-456

Purpose: Mouse monoclonal antibody raised against a full length recombinant RUVBL1.

Sequence: MKIEEVKSTT KTQRIASHSH VKGLGLDESG LAKQAASGLV GQENAREACG VIVELIKSKK MAGRAVLLAG PPGTGKTALA LAIAQELGSK VPFCPMVGSE VYSTEIKKTE VLMENFRRAI GLRIKETKEV YEGEVTELTP CETENPMGGY GKTISHVIIG LKTAKGTKQL KLDPSIFESL QKERVEAGDV IYIEANSGAV KRQGRCDTYA TEFDLEAEEY VPLPKGDVHK KKEIIQDVTL HDLDVANARP QGGQDILSMM GQLMKPKKTE ITDKLRGEIN KVVNKYIDQG IAELVPGVLF VDEVHMLDIE CFTYLHRALE SSIAPIVIFA SNRGNCVIRG TEDITSPHGI PLDLLDRVMI IRTMLYTPQE MKQIIKIRAQ TEGINISEEA LNHLGEIGTK TTLRYSVQLL TPANLLAKIN GKDSIEKEHV EEISELFYDA KSSAKILADQ QDKYMK

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RUVBL1 (AAH02993, 1 a.a. ~ 456 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RUVBL1 antibody (ABIN563710)

Kaji, Fertig, Medsger, Satoh, Hoshino, Hamaguchi, Hasegawa, Lucas, Schnure, Ogawa, Sato, Takehara, Fujimoto, Kuwana: "Autoantibodies to RuvBL1 and RuvBL2: a novel systemic sclerosis-related antibody associated with diffuse cutaneous and skeletal muscle involvement." in: Arthritis care & research, Vol. 66, Issue 4, pp. 575-84, (2014) (PubMed).

Target Details for RUVBL1

Target: RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))

Alternative Name: RUVBL1

Background: Full Gene Name: RuvB-like 1 (E. coli)
Synonyms: ECP54,INO80H,NMP238,PONTIN,Pontin52,RVB1,TIH1,TIP49,TIP49A

Gene ID: 8607

Pathways: Telomere Maintenance