RIOK3 antibody (AA 1-516)

Catalog No. ABIN563783

The Mouse Monoclonal anti-RIOK3 antibody has been validated for WB, ELISA and IP. It is suitable to detect RIOK3 in samples from Human. There are 2+ publications available.

Quick Overview for RIOK3 antibody (AA 1-516) (ABIN563783)

Target: RIOK3 (RRIO Kinase 3 (RIOK3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RIOK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Clone: 4A12-1D2

Product Details anti-RIOK3 Antibody

Binding Specificity: AA 1-516

Purpose: Mouse monoclonal antibody raised against a full length recombinant RIOK3.

Sequence: MDLVGVASPE PGTAAAWGPS KCPWAIPQNT ISCSLADVMS EQLAKELQLE EEAAVFPEVA VAEGPFITGE NIDTSSDLML AQMLQMEYDR EYDAQLRREE KKFNGDSKVS ISFENYRKVH PYEDSDSSED EVDWQDTRDD PYRPAKPVPT PKKGFIGKGK DITTKHDEVV CGRKNTARME NFAPEFQVGD GIGMDLKLSN HVFNALKQHA YSEERRSARL HEKKEHSTAE KAVDPKTRLL MYKMVNSGML ETITGCISTG KESVVFHAYG GSMEDEKEDS KVIPTECAIK VFKTTLNEFK NRDKYIKDDF RFKDRFSKLN PRKIIRMWAE KEMHNLARMQ RAGIPCPTVV LLKKHILVMS FIGHDQVPAP KLKEVKLNSE EMKEAYYQTL HLMRQLYHEC TLVHADLSEY NMLWHAGKVW LIDVSQSVEP THPHGLEFLF RDCRNVSQKG GVKEALSERE LFNAVSGLNI TADNEADFLA EIEALEKMNE DHVQKNGRKA ASFLKDDGDP PLLYDE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RIOK3 (AAH39729, 1 a.a. ~ 516 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RIOK3 antibody (ABIN563783)

Singleton, Rouhi, Zois, Haider, Li, Kessler, Cao, Harris: "Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis." in: Oncogene, (2014) (PubMed).

Kimmelman, Hezel, Aguirre, Zheng, Paik, Ying, Chu, Zhang, Sahin, Yeo, Ponugoti, Nabioullin, Deroo, Yang, Wang, McGrath, Protopopova, Ivanova, Zhang, Feng, Tsao, Redston, Protopopov, Xiao, Futreal et al.: "Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 49, pp. 19372-7, (2008) (PubMed).

Target Details for RIOK3

Target: RIOK3 (RRIO Kinase 3 (RIOK3))

Alternative Name: RIOK3

Background: Full Gene Name: RIO kinase 3 (yeast)
Synonyms: DKFZp779L1370,SUDD

Gene ID: 8780