USP14 antibody (AA 395-494)

Catalog No. ABIN563939

The Mouse Monoclonal anti-USP14 antibody has been validated for WB, ELISA and IF. It is suitable to detect USP14 in samples from Human. There is 1 publication available.

Quick Overview for USP14 antibody (AA 395-494) (ABIN563939)

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This USP14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 6D6

Product Details anti-USP14 Antibody

Binding Specificity: AA 395-494

Purpose: Mouse monoclonal antibody raised against a partial recombinant USP14.

Sequence: PQKEVKYEPF SFADDIGSNN CGYYDLQAVL THQGRSSSSG HYVSWVKRKQ DEWIKFDDDK VSIVTPEDIL RLSGGGDWHI AYVLLYGPRR VEIMEEESEQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: USP14 (NP_005142, 395 a.a. ~ 494 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-USP14 antibody (ABIN563939)

Hyrskyluoto, Bruelle, Lundh, Do, Kivinen, Rappou, Reijonen, Waltimo, Petersén, Lindholm, Korhonen: "Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1?." in: Human molecular genetics, Vol. 23, Issue 22, pp. 5928-39, (2014) (PubMed).

Target Details for USP14

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Alternative Name: USP14

Background: Full Gene Name: ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
Synonyms: TGT

Gene ID: 9097

NCBI Accession: NM_005151