TCIRG1 antibody (AA 121-220)

Catalog No. ABIN564479

There are 3+ publications for this product available. The Mouse Monoclonal anti-TCIRG1 antibody is suitable to detect TCIRG1 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for TCIRG1 antibody (AA 121-220) (ABIN564479)

Target: TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCIRG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6H3

Product Details anti-TCIRG1 Antibody

Binding Specificity: AA 121-220

Purpose: Mouse monoclonal antibody raised against a partial recombinant TCIRG1.

Sequence: QLHQLQLHAA VLRQGHEPQL AAAHTDGASE RTPLLQAPGG PHQDLRVNFV AGAVEPHKAP ALERLLWRAC RGFLIASFRE LEQPLEHPVT GEPATWMTFL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TCIRG1 (AAH18133, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TCIRG1 antibody (ABIN564479)

Henriksen, Andreassen, Thudium, Gudmann, Moscatelli, Crüger-Hansen, Schulz, Dziegiel, Richter, Karsdal, Neutzsky-Wulff: "A specific subtype of osteoclasts secretes factors inducing nodule formation by osteoblasts." in: Bone, Vol. 51, Issue 3, pp. 353-61, (2012) (PubMed).

Schinke, Schilling, Baranowsky, Seitz, Marshall, Linn, Blaeker, Huebner, Schulz, Simon, Gebauer, Priemel, Kornak, Perkovic, Barvencik, Beil, Del Fattore, Frattini, Streichert, Pueschel, Villa et al.: "Impaired gastric acidification negatively affects calcium homeostasis and bone mass. ..." in: Nature medicine, Vol. 15, Issue 6, pp. 674-81, (2009) (PubMed).

Schulz, Dave, Stehberger, Chau, Wagner: "Differential localization of vacuolar H+-ATPases containing a1, a2, a3, or a4 (ATP6V0A1-4) subunit isoforms along the nephron." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 20, Issue 1-4, pp. 109-20, (2007) (PubMed).

Target Details for TCIRG1

Target: TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))

Alternative Name: TCIRG1

Background: Full Gene Name: T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
Synonyms: ATP6N1C,ATP6V0A3,Atp6i,OC-116 kDa,OC116,OPTB1,Stv1,TIRC7,Vph1,a3

Gene ID: 10312

Pathways: Transition Metal Ion Homeostasis, Proton Transport