AKR1A1 antibody (AA 1-325)

Catalog No. ABIN564487

This Mouse Monoclonal antibody specifically detects AKR1A1 in WB, ELISA and IHC (p). It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for AKR1A1 antibody (AA 1-325) (ABIN564487)

Target: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AKR1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1A11-2A4

Product Details anti-AKR1A1 Antibody

Binding Specificity: AA 1-325

Purpose: Mouse monoclonal antibody raised against a full length recombinant AKR1A1.

Sequence: MAASCVLLHT GQKMPLIGLG TWKSEPGQVK AAVKYALSVG YRHIDCAAIY GNEPEIGEAL KEDVGPGKAV PREELFVTSK LWNTKHHPED VEPALRKTLA DLQLEYLDLY LMHWPYAFER GDNPFPKNAD GTICYDSTHY KETWKALEAL VAKGLVQALG LSNFNSRQID DILSVASVRP AVLQVECHPY LAQNELIAHC QARGLEVTAY SPLGSSDRAW RDPDEPVLLE EPVVLALAEK YGRSPAQILL RWQVQRKVIC IPKSITPSRI LQNIKVFDFT FSPEEMKQLN ALNKNWRYIV PMLTVDGKRV PRDAGHPLYP FNDPY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: AKR1A1 (AAH00670, 1 a.a. ~ 325 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-AKR1A1 antibody (ABIN564487)

Singer, Herth, Kuhlmann, Holland-Nell, Beck-Sickinger, Hoffmann: "Mapping of phosphorylation-dependent anti-tau monoclonal antibodies in immunoblots using human tau-constructs synthesized by native chemical ligation." in: Biochemical and biophysical research communications, Vol. 367, Issue 2, pp. 318-22, (2008) (PubMed).

Bains, Takahashi, Pfeifer, Grigliatti, Reid, Riggs: "Two allelic variants of aldo-keto reductase 1A1 exhibit reduced in vitro metabolism of daunorubicin." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 36, Issue 5, pp. 904-10, (2008) (PubMed).

Takahashi, Bains, Pfeifer, Grigliatti, Reid, Riggs: "Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 36, Issue 6, pp. 991-4, (2008) (PubMed).

Target Details for AKR1A1

Target: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Alternative Name: AKR1A1

Background: Full Gene Name: aldo-keto reductase family 1, member A1 (aldehyde reductase)
Synonyms: ALDR1,ALR,ARM,DD3,MGC12529,MGC1380

Gene ID: 10327

Pathways: Monocarboxylic Acid Catabolic Process